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Michelle Seagull had been serving as the agency's acting commissioner since Jonathan Harris’ resignation last month.
At present there are more than 15,000 medical marijuana patients in the state and nearly 600 physicians registered to treat patients.
Connecticut is on pace to record 888 drug overdoses this year, compared with 729 in 2015 and 568 in 2014.
The legal marijuana market in the U.S. could be worth nearly $23 billion by 2020.